This is one of the most discussed topics especially in Clinical Genomics! Affordability, accuracy, feasibility and of course time consumption - based on these factor mostly, which sequencing technology is more suitable for clinics? Whole Exome Sequencing or Whole Genome Sequencing? (WGS or WES, WGS vs WES) So here's my 2 cents on this discussion! When it comes to DNA sequencing there has always been a raging debate over the choice of Whole Genome Sequencing (WGS) or Whole Exome Sequencing (WXS) for routine use. Whole genome sequencing (WGS), as the name suggests is the process of obtaining the entire genome. In most cases however, this is far from practical and only 95-97% of the genome is covered because it is technically difficult to sequence certain regions of the genome (high GC content, large repeat regions, centromeres, telomeres, etc.) with existing technology. “It’s very fair to say the human genome was never fully sequenced,” - Craig Venter “The human genome ha
MH370 A different point of view Here are the excerpts from an article by a pilot called Chris Goodfellow which make sense in my head and I thought it would make sense to many of my friends with a similar wavelength! Here we go! A lot of speculation about MH370. Terrorism, hijack, meteors. I cannot believe the analysis on CNN - almost disturbing. There could be a more simple explanation of this event. Loaded 777 departs midnight from Kuala to Beijing. Hot night. Heavy aircraft. About an hour out across the gulf towards Vietnam the plane goes dark meaning the transponder goes off and secondary radar tracking goes off. Two days later we hear of reports that Malaysian military radar (which is a primary radar meaning the plane is being tracked by reflection rather than by transponder interrogation response) has tracked the plane on a southwesterly course back across the Malay Peninsula into the straits of Malacca. When I heard this I immediately brought up Google Earth and I